Reishi Research Database
Comprehensive Scientific Studies on Ganoderma lucidum
12+ peer-reviewed studies documenting Reishi's immune support, cardiovascular health, and cancer treatment adjunct benefits.
Research Categories
Human Clinical Trials
Landmark human studies demonstrating Reishi's health benefits in real-world applications.
Gulf War Illness Study (2021)
Placebo-controlled, pseudo-randomized, crossover trialKey Outcomes:
- Improved quality of life measures
- Reduced fatigue and cognitive symptoms
- Enhanced immune function markers
- Well-tolerated with no adverse effects
Citation: A Placebo-Controlled, Pseudo-Randomized, Crossover Trial of Botanical Agents for Gulf War Illness: Reishi Mushroom (Ganoderma lucidum), Stinging Nettle (Urtica dioica), and Epimedium (Epimedium sagittatum). Journal of Alternative and Complementary Medicine, 2021.
Cancer Treatment Studies
Research demonstrating Reishi's anti-cancer properties and potential as a treatment adjunct.
Cancer Cell Growth Inhibition (2011)
In vitro and in vivo studyKey Findings:
- Inhibition of cancer cell proliferation
- Reduced expression of key cancer molecules
- Anti-inflammatory effects in cancer tissue
- Potential for breast cancer treatment adjunct
Citation: Ganoderma lucidum (Reishi) inhibits cancer cell growth and expression of key molecules in inflammatory breast cancer. Nutrition and Cancer, 63(7), 1085-1094.
Anti-Tumor Effects (2013)
In vivo and in vitro studyKey Findings:
- Reduced tumor growth in animal models
- Enhanced immune response against cancer
- Anti-angiogenic effects
- Potential for cancer treatment adjunct
Citation: Anti-tumor effects of Ganoderma lucidum (reishi) in inflammatory breast cancer in in vivo and in vitro models. PLoS One, 8(2), e57431.
Cardiovascular Health Studies
Research demonstrating Reishi's benefits for heart health and metabolic disease risk.
Cardiovascular and Metabolic Benefits (2021)
Systematic review and meta-analysisKey Findings:
- Reduced cardiovascular disease risk factors
- Improved lipid profiles and cholesterol levels
- Enhanced blood pressure regulation
- Potential for metabolic syndrome management
Citation: The beneficial effects of Ganoderma lucidum on cardiovascular and metabolic disease risk. International Journal of Environmental Research and Public Health, 18(7), 3671.
Immune System Studies
Research demonstrating Reishi's immune modulation and support mechanisms.
Quality Consistency Study (2017)
Quality assessment studyKey Findings:
- Significant variation in product quality
- Importance of standardized extracts
- Need for quality control in supplements
- Consumer education on product selection
Citation: Evaluation on quality consistency of Ganoderma lucidum dietary supplements collected in the United States. Scientific Reports, 7, 7792.
Research Summary
Evidence Level
Moderate to Strong - Promising clinical trials with supporting in vitro and animal studies
Mechanism
Well-Understood - Triterpenes and polysaccharides modulate immune and cardiovascular function
Safety
Excellent - No significant side effects reported in clinical studies
Dosage
Established - 1-3g/day effective dose range for immune and cardiovascular support
Bioactive Compounds
The science behind Reishi's stress-relief and immune benefits
Triterpenes
Bitter compounds that support liver function and help regulate the body's stress response system.
Learn MoreGanoderic Acids
Unique compounds that support liver health, cholesterol management, and cardiovascular wellness.
Learn MoreClinical Research
Scientific evidence supporting Reishi benefits
Stress & Sleep Study
Clinical trials showed significant improvements in sleep quality and stress markers in participants taking Reishi extract.
Immune Function Research
Studies demonstrate Reishi's ability to enhance immune cell activity and overall immune response.
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