LyfeBrew Changa Research Citations

Scientific Research Citations from PubMed Central

This page contains peer-reviewed scientific citations for Reishi mushroom research. Each citation links directly to the full study on PubMed Central.

Note: Citations are organized by relevance and include study titles, authors, publication details, and direct links to full-text articles.
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LyfeBrew Changa Research Citations

LyfeBrew Changa Research Citations

Scientific Research Citations from PubMed Central

This page contains peer-reviewed scientific citations for Reishi mushroom research. Each citation links directly to the full study on PubMed Central.

Note: Citations are organized by relevance and include study titles, authors, publication details, and direct links to full-text articles.
Loading: Citations are being loaded from the source file. This may take a moment for large files.
  • 1.
    Revitalization of the Endophytic Fungus Acremonium sp. MEP2000 and Its Impact on the Growth and Accumulation of Bioactive Compounds in Inonotus obliquus.
    Wu H, et al.
    J Microbiol Biotechnol. 2025.
    PMCID: PMC11876012
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Revitalization of the Endophytic Fungus Acremonium sp. MEP2000 and Its Impact on the Growth and Accumulation of Bioactive Compounds in Inonotus obliquus .. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Research article (type not explicit in title). Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Outcomes and methods described in the paper’s Results/Methods sections. Open article.
    • Why might this paper be useful to readers? Gives context for future research, product development, or cultivation/process decisions. Open article.
  • 2.
    Anticancer potentials of chaga and notoginseng against dog bladder cancer organoids.
    Shinohara Y, et al.
    J Vet Med Sci. 2025.
    PMCID: PMC11830434
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Anticancer potentials of chaga and notoginseng against dog bladder cancer organoids.. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Research article (type not explicit in title). Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Outcomes and methods described in the paper’s Results/Methods sections. Open article.
    • Why might this paper be useful to readers? Gives context for future research, product development, or cultivation/process decisions. Open article.
  • 3.
    Fungal polysaccharides from Inonotus obliquus are agonists for Toll-like receptors and induce macrophage anti-cancer activity.
    Wold CW, et al.
    Commun Biol. 2024.
    PMCID: PMC10891174
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Fungal polysaccharides from Inonotus obliquus are agonists for Toll-like receptors and induce macrophage anti-cancer activity.. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Research article (type not explicit in title). Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Outcomes and methods described in the paper’s Results/Methods sections. Open article.
    • Why might this paper be useful to readers? Clarifies how specific mushroom compounds are produced, measured, or function in research settings. Open article.
  • 4.
    Synergistic Cytotoxicity of Extracts of Chaga Mushroom and Microalgae against Mammalian Cancer Cells In Vitro.
    Wagle S, et al.
    Oxid Med Cell Longev. 2024.
    PMCID: PMC10807943
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Synergistic Cytotoxicity of Extracts of Chaga Mushroom and Microalgae against Mammalian Cancer Cells In Vitro.. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Cell-based (in vitro) study. Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Cell viability, signaling/gene expression, and functional assays. Open article.
    • Why might this paper be useful to readers? Gives context for future research, product development, or cultivation/process decisions. Open article.
  • 5.
    Inonotus obliquus upregulates muscle regeneration and augments function through muscle oxidative metabolism.
    You CL, et al.
    Int J Biol Sci. 2023.
    PMCID: PMC10539711
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Inonotus obliquus upregulates muscle regeneration and augments function through muscle oxidative metabolism.. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Animal (in vivo) study. Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Biomarkers, histology, behavior/physiology, and dose–response in animals. Open article.
    • Why might this paper be useful to readers? Gives context for future research, product development, or cultivation/process decisions. Open article.
  • 6.
    Integrated omic profiling of the medicinal mushroom Inonotus obliquus under submerged conditions.
    Hao J, et al.
    BMC Genomics. 2023.
    PMCID: PMC10507853
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Integrated omic profiling of the medicinal mushroom Inonotus obliquus under submerged conditions.. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Animal (in vivo) study. Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Biomarkers, histology, behavior/physiology, and dose–response in animals. Open article.
    • Why might this paper be useful to readers? Gives context for future research, product development, or cultivation/process decisions. Open article.
  • 7.
    Protective Effects of Lanostane Triterpenoids from Chaga Mushroom in Human Keratinocytes, HaCaT Cells, against Inflammatory and Oxidative Stresses.
    Park J, et al.
    Int J Mol Sci. 2023.
    PMCID: PMC10454022
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Protective Effects of Lanostane Triterpenoids from Chaga Mushroom in Human Keratinocytes, HaCaT Cells, against Inflammatory and Oxidative Stresses.. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Cell-based (in vitro) study. Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Cell viability, signaling/gene expression, and functional assays. Open article.
    • Why might this paper be useful to readers? Clarifies how specific mushroom compounds are produced, measured, or function in research settings. Open article.
  • 8.
    Comparison of Bioactive Secondary Metabolites and Cytotoxicity of Extracts from Inonotus obliquus Isolates from Different Host Species.
    Sułkowska-Ziaja K, et al.
    Molecules. 2023.
    PMCID: PMC10343780
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Comparison of Bioactive Secondary Metabolites and Cytotoxicity of Extracts from Inonotus obliquus Isolates from Different Host Species.. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Research article (type not explicit in title). Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Outcomes and methods described in the paper’s Results/Methods sections. Open article.
    • Why might this paper be useful to readers? Gives context for future research, product development, or cultivation/process decisions. Open article.
  • 9.
    Methanol extract of Inonotus obliquus improves type 2 diabetes mellitus through modifying intestinal flora.
    Ye X, et al.
    Front Endocrinol (Lausanne). 2023.
    PMCID: PMC9852891
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Methanol extract of Inonotus obliquus improves type 2 diabetes mellitus through modifying intestinal flora.. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Research article (type not explicit in title). Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Outcomes and methods described in the paper’s Results/Methods sections. Open article.
    • Why might this paper be useful to readers? Gives context for future research, product development, or cultivation/process decisions. Open article.
  • 10.
    Microporous Biocarbons Derived from Inonotus obliquus Mushroom and Their Application in the Removal of Liquid and Gaseous Impurities.
    Bazan-Wozniak A, et al.
    Int J Mol Sci. 2022.
    PMCID: PMC9779400
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Microporous Biocarbons Derived from Inonotus obliquus Mushroom and Their Application in the Removal of Liquid and Gaseous Impurities.. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Research article (type not explicit in title). Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Outcomes and methods described in the paper’s Results/Methods sections. Open article.
    • Why might this paper be useful to readers? Gives context for future research, product development, or cultivation/process decisions. Open article.
Page 2
  • 11.
    Carbon Source Affects Synthesis, Structures, and Activities of Mycelial Polysaccharides from Medicinal Fungus Inonotus obliquus.
    He H, et al.
    J Microbiol Biotechnol. 2021.
    PMCID: PMC9705997
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Carbon Source Affects Synthesis, Structures, and Activities of Mycelial Polysaccharides from Medicinal Fungus Inonotus obliquus .. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Research article (type not explicit in title). Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Outcomes and methods described in the paper’s Results/Methods sections. Open article.
    • Why might this paper be useful to readers? Clarifies how specific mushroom compounds are produced, measured, or function in research settings. Open article.
  • 12.
    Comparative Analyses of Bioactive Compounds in Inonotus obliquus Conks Growing on Alnus and Betula.
    Drenkhan R, et al.
    Biomolecules. 2022.
    PMCID: PMC9496626
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Comparative Analyses of Bioactive Compounds in Inonotus obliquus Conks Growing on Alnus and Betula .. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Animal (in vivo) study. Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Biomarkers, histology, behavior/physiology, and dose–response in animals. Open article.
    • Why might this paper be useful to readers? Gives context for future research, product development, or cultivation/process decisions. Open article.
  • 13.
    Evaluation of Toxicity and Efficacy of Inotodiol as an Anti-Inflammatory Agent Using Animal Model.
    Nguyen TMN, et al.
    Molecules. 2022.
    PMCID: PMC9331631
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Evaluation of Toxicity and Efficacy of Inotodiol as an Anti-Inflammatory Agent Using Animal Model.. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Research article (type not explicit in title). Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Outcomes and methods described in the paper’s Results/Methods sections. Open article.
    • Why might this paper be useful to readers? Gives context for future research, product development, or cultivation/process decisions. Open article.
  • 14.
    Genome sequencing of Inonotus obliquus reveals insights into candidate genes involved in secondary metabolite biosynthesis.
    Duan Y, et al.
    BMC Genomics. 2022.
    PMCID: PMC9020118
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Genome sequencing of Inonotus obliquus reveals insights into candidate genes involved in secondary metabolite biosynthesis.. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Omics/profiling or bioinformatics study. Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Outcomes and methods described in the paper’s Results/Methods sections. Open article.
    • Why might this paper be useful to readers? Gives context for future research, product development, or cultivation/process decisions. Open article.
  • 15.
    Interference of Chaga mushroom terpenoids with the attachment of SARS-CoV-2; in silico perspective.
    Elshemey WM, et al.
    Comput Biol Med. 2022.
    PMCID: PMC8988443
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Interference of Chaga mushroom terpenoids with the attachment of SARS-CoV-2; in silico perspective.. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Research article (type not explicit in title). Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Outcomes and methods described in the paper’s Results/Methods sections. Open article.
    • Why might this paper be useful to readers? Gives context for future research, product development, or cultivation/process decisions. Open article.
  • 16.
    Supercritical CO2 Extraction of Triterpenoids from Chaga Sterile Conk of Inonotus obliquus.
    Huynh N, et al.
    Molecules. 2022.
    PMCID: PMC8955864
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Supercritical CO 2 Extraction of Triterpenoids from Chaga Sterile Conk of Inonotus obliquus .. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Extraction/process optimization. Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Yield comparisons, parameter optimization, and scalability considerations. Open article.
    • Why might this paper be useful to readers? Clarifies how specific mushroom compounds are produced, measured, or function in research settings. Open article.
  • 17.
    Chaga mushroom-induced oxalate nephropathy that clinically manifested as nephrotic syndrome: A case report.
    Kwon O, et al.
    Medicine (Baltimore). 2022.
    PMCID: PMC8913114
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Chaga mushroom-induced oxalate nephropathy that clinically manifested as nephrotic syndrome: A case report.. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Human clinical study (trial/pilot). Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Outcomes and methods described in the paper’s Results/Methods sections. Open article.
    • Why might this paper be useful to readers? Gives context for future research, product development, or cultivation/process decisions. Open article.
  • 18.
    Biological Synthesis of Bioactive Gold Nanoparticles from Inonotus obliquus for Dual Chemo-Photothermal Effects against Human Brain Cancer Cells.
    Shukurov I, et al.
    Int J Mol Sci. 2022.
    PMCID: PMC8880898
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Biological Synthesis of Bioactive Gold Nanoparticles from Inonotus obliquus for Dual Chemo-Photothermal Effects against Human Brain Cancer Cells.. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Cell-based (in vitro) study. Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Cell viability, signaling/gene expression, and functional assays. Open article.
    • Why might this paper be useful to readers? Gives context for future research, product development, or cultivation/process decisions. Open article.
  • 19.
    Inotodiol From Inonotus obliquus Chaga Mushroom Induces Atypical Maturation in Dendritic Cells.
    Maza PAMA, et al.
    Front Immunol. 2021.
    PMCID: PMC7994266
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Inotodiol From Inonotus obliquus Chaga Mushroom Induces Atypical Maturation in Dendritic Cells.. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Cell-based (in vitro) study. Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Cell viability, signaling/gene expression, and functional assays. Open article.
    • Why might this paper be useful to readers? Gives context for future research, product development, or cultivation/process decisions. Open article.
  • 20.
    Inonotus obliquus extract alleviates myocardial ischemia/reperfusion injury by suppressing endoplasmic reticulum stress.
    Wu Y, et al.
    Mol Med Rep. 2020.
    PMCID: PMC7716405
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Inonotus obliquus extract alleviates myocardial ischemia/reperfusion injury by suppressing endoplasmic reticulum stress.. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Research article (type not explicit in title). Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Outcomes and methods described in the paper’s Results/Methods sections. Open article.
    • Why might this paper be useful to readers? Gives context for future research, product development, or cultivation/process decisions. Open article.
Page 3
  • 21.
    Extracts of Phellinus linteus, Bamboo (Sasa senanensis) Leaf and Chaga Mushroom (Inonotus obliquus) Exhibit Antitumor Activity through Activating Innate Immunity.
    Fang J, et al.
    Nutrients. 2020.
    PMCID: PMC7469031
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Extracts of Phellinus linteus , Bamboo ( Sasa senanensis ) Leaf and Chaga Mushroom ( Inonotus obliquus ) Exhibit Antitumor Activity through Activating Innate Immunity.. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Research article (type not explicit in title). Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Outcomes and methods described in the paper’s Results/Methods sections. Open article.
    • Why might this paper be useful to readers? Gives context for future research, product development, or cultivation/process decisions. Open article.
  • 22.
    Development of End Stage Renal Disease after Long-Term Ingestion of Chaga Mushroom: Case Report and Review of Literature.
    Lee S, et al.
    J Korean Med Sci. 2020.
    PMCID: PMC7234858
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Development of End Stage Renal Disease after Long-Term Ingestion of Chaga Mushroom: Case Report and Review of Literature.. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Review or meta-analysis. Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Biomarkers, histology, behavior/physiology, and dose–response in animals. Open article.
    • Why might this paper be useful to readers? Gives context for future research, product development, or cultivation/process decisions. Open article.
  • 23.
    Renoprotective Impacts of Inonotus obliquus Ethanol-Ethyl Acetate Extract on Combined Streptozotocin and Unilateral Nephrectomy-Induced Diabetic Nephropathy in Mice.
    Chiang KH, et al.
    Int J Mol Sci. 2023.
    PMCID: PMC10002342
    Quick FAQ for this paper (4 questions)
    • What does this article investigate or review? From the title, it focuses on: Renoprotective Impacts of Inonotus obliquus Ethanol-Ethyl Acetate Extract on Combined Streptozotocin and Unilateral Nephrectomy-Induced Diabetic Nephropathy in Mice.. See the full text for detailed methods and results. Open article.
    • What kind of study is it? Animal (in vivo) study. Check the paper’s Methods for design and protocols. Open article.
    • What outcomes or endpoints are typically reported? Biomarkers, histology, behavior/physiology, and dose–response in animals. Open article.
    • Why might this paper be useful to readers? Gives context for future research, product development, or cultivation/process decisions. Open article.

© 2025 LyfeBrew. Scientific research citations compiled from PubMed Central.