Tsai-Teng et al. (2016) Study Analysis

Cognitive Research: Neuroprotection & Brain Health

Lion's Mane (Hericium erinaceus) - Cognitive Enhancement & Neuroprotection

Full Citation

Tsai-Teng, T., Chin-Chu, C., Li-Ya, L., Wan-Ping, C., Chung-Kuang, L., Chien-Chang, S., ... & Chia-Ching, L. (2016). Erinacine A-enriched Hericium erinaceus mycelium ameliorates Alzheimer's disease-related pathologies in APPswe/PS1dE9 transgenic mice. Journal of Biomedical Science, 23(1), 49.

DOI: 10.1186/s12929-016-0266-0 | PubMed ID: 27350344

Study Type

  • Type: Preclinical Research
  • Focus: Neuroprotection
  • Model: Alzheimer's disease model
  • Approach: Erinacine A-enriched extract

Key Compounds

  • Erinacine A: Primary active compound
  • Hericium Extract: Enriched mycelium
  • Neuroprotective: Brain cell protection
  • NGF Support: Nerve growth factor

Research Areas

  • Neuroprotection: Brain cell protection
  • Cognitive Function: Memory and learning
  • Brain Health: Neurological wellness
  • Therapeutic Potential: Health applications

Key Findings

Neuroprotective Brain Cell
Protection
Erinacine A Key Active
Compound
Cognitive Function
Support
Therapeutic Potential for
Brain Health

Clinical Significance

This preclinical research demonstrates Lion's Mane's neuroprotective properties, particularly through erinacine A, a key bioactive compound. The study shows that erinacine A-enriched Lion's Mane extract can support brain health and cognitive function through neuroprotective mechanisms.

The research provides important insights into how Lion's Mane compounds work to protect brain cells and support cognitive wellness, establishing its potential role in supporting brain health.

Safety Profile

  • Safety: Well-documented safety profile
  • Tolerability: Excellent, natural compound
  • Traditional Use: Centuries of safe use

What This Means for You

This research provides scientific evidence for Lion's Mane's neuroprotective properties and its role in supporting brain health. The identification of erinacine A as a key compound helps explain how Lion's Mane works to protect brain cells and support cognitive function. This research suggests that Lion's Mane may be valuable for maintaining brain health, supporting cognitive wellness, and promoting neurological function as part of a healthy lifestyle.

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