Tsukagoshi et al. (1984) Study Analysis

Landmark Phase III Trial: PSK Cancer Treatment Adjunct

Turkey Tail (Trametes versicolor) - PSK Research

Study Overview

This landmark Phase III clinical trial was instrumental in gaining PSK (polysaccharide-K) approval in Japan as a cancer treatment adjunct. The study demonstrated improved 5-year survival rates when PSK was combined with chemotherapy.

Key Focus: Cancer treatment adjunct, immune support, PSK/PSP compounds

Study Type: Phase III clinical trial

Year: 1984

Significance: Led to PSK approval in Japan for cancer treatment

Study Type

  • Type: Phase III clinical trial
  • Focus: Cancer treatment adjunct
  • Compound: PSK (polysaccharide-K)
  • Source: Turkey Tail mushroom

Treatment

  • Intervention: PSK + Chemotherapy
  • Comparison: Chemotherapy alone
  • Outcome: Survival rates

Impact

  • Result: Improved 5-year survival
  • Approval: PSK approved in Japan
  • Significance: Landmark study

Primary Results

Improved 5-Year Survival
Rates
Approved PSK in Japan
As Adjunct
Phase III Clinical Trial
Landmark Study

Key Findings

  • Survival Improvement: The study demonstrated improved 5-year survival rates when PSK was combined with chemotherapy compared to chemotherapy alone
  • Regulatory Approval: This research was instrumental in gaining PSK approval in Japan as an official cancer treatment adjunct
  • Immune Support: PSK's immune-modulating properties were shown to support the body during cancer treatment
  • Clinical Significance: This Phase III trial established PSK as a recognized complementary therapy for cancer treatment

Clinical Significance

This landmark study represents a major milestone in functional mushroom research. The Phase III trial demonstrated that PSK from Turkey Tail mushroom could improve survival outcomes when used alongside conventional cancer treatment. This research led to PSK being officially approved in Japan as a cancer treatment adjunct, making it one of the few mushroom-derived compounds to receive such recognition.

The study's findings support the use of Turkey Tail's PSK compounds for immune support, particularly in the context of supporting the body during challenging health conditions. While this research focused on cancer treatment, it also demonstrates the powerful immune-modulating properties of Turkey Tail mushrooms.

What This Means for You

This landmark research demonstrates the powerful immune-supporting properties of Turkey Tail mushrooms, particularly through PSK compounds. While this study focused on cancer treatment support, it highlights Turkey Tail's ability to modulate and strengthen immune function. For general immune health and wellness, Turkey Tail can help support your body's natural defense systems. It's important to note that this research was conducted in a medical context, and Turkey Tail supplements should be viewed as supportive to overall wellness rather than a treatment for medical conditions.

Turkey Tail Products

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